Posted inBiotechnology & Genetics
Evolutionarily conserved short linear motifs drive actin filament binding
Pipeline overviewThe SLiMFold pipeline, which integrates multiple bioinformatic tools to systematically identify, filter and validate…
Posted inBiotechnology & Genetics
Non-canonical gene amplifications facilitate adaptive evolution in bacteria
Sandegren, L. & Andersson, D. I. Bacterial gene amplification: implications for the evolution of antibiotic…
Posted inBiotechnology & Genetics
New ddPCR Method for Root DNA Analysis
“It’s a bit like giving the soil a DNA test.” A new droplet digital PCR…
Posted inBiotechnology & Genetics
Pregnancy-induced tissue-resident memory-like T cells contribute to tumor control in breast cancer
Rosenberg, L., Thalib, L., Adami, H. O. & Hall, P. Childbirth and breast cancer prognosis.…
Posted inBiotechnology & Genetics
CHIME: a novel HLA eplet model associates with non-relapse mortality in haploidentical hematopoietic cell transplant with post-transplant cyclophosphamide
Pidala J, Lee SJ, Ahn KW, Spellman S, Wang HL, Aljurf M, et al. Nonpermissive…
Posted inBiotechnology & Genetics
Exhausted CD8+ T cell subsets differ a TAD
Exhausted CD8+ T cell subsets differ a TAD
Posted inBiotechnology & Genetics
Mapping self-associating chromatin hubs identifies Id proteins as key determinants of exhausted CD8+ T cell fate
McLane, L. M., Abdel-Hakeem, M. S. & Wherry, E. J. CD8 T cell exhaustion during…
Posted inBiotechnology & Genetics
Promoter reinforcement supports transcriptional resilience in drug-resistant cancer
Transcriptomic restoration is a hallmark of drug-resistant cancer cellsTo define transcriptional changes associated with drug…
Posted inBiotechnology & Genetics
Clocked stepping of an artificial protein walker along a DNA track
Construct design and cloningProtein constructs were based on DtxR (residues 2–121 with a C102D mutation…
Posted inBiotechnology & Genetics
Mechanics and engineering models of tissue remodelling during tumour progression
Linke, J. A., Munn, L. L. & Jain, R. K. Compressive stresses in cancer: characterization…